@article{PAR00012813,
  title = {{C}ausal analysis of {H}1{N}1pdm09 influenza infection risk in a household cohort},
  author = {{M}ansiaux, {Y}. and {S}alez, {N}. and {L}apidus, {N}. and {S}etbon, {M}. and {A}ndreoletti, {L}. and {L}eruez-{V}ille, {M}. and {C}auchemez, {S}. and {G}ougeon, {M}. {L}. and {V}ely, {F}. and {S}chwarzinger, {M}. and {A}bel, {L}. and {D}elabre, {R}. {M}. and {F}lahault, {A}. and de {L}amballerie, {X}avier and {C}arrat, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {O}btaining a comprehensive quantitative figure of the determinants of influenza infection will help identify priority targets for future influenza mitigation interventions. {W}e developed an original causal model integrating highly diverse factors and their dependencies, to identify the most critical determinants of pandemic influenza infection ({H}1{N}1pdm09) during the 2010-2011 influenza season. {M}ethods {W}e used data from 601 households (1450 participants) included in a dedicated cohort. {S}tructural equations were used to model direct and indirect relationships between infection and risk perception, compliance with preventive behaviours, social contacts, indoor and outdoor environment, sociodemographic factors and pre-epidemic host susceptibility. {S}tandardised estimates (beta(std)) were used to assess the strength of associations (ranging from -1 for a completely negative association to 1 for a completely positive association). {R}esults {H}ost susceptibility to {H}1{N}1pdm09 and compliance with preventive behaviours were the only two factors directly associated with the infection risk (beta(std)=0.31 and beta(std)=-0.21). {C}ompliance with preventive behaviours was influenced by risk perception and preventive measures perception (beta(std)=0.14 and beta(std)=0.27). {T}he number and duration of social contacts were not associated with {H}1{N}1pdm09 infection. {C}onclusions {O}ur findings suggest that influenza vaccination in addition to public health communication campaigns focusing on personal preventive measures should be prioritised as potentially efficient interventions to mitigate influenza epidemics.},
  keywords = {{FRANCE}},
  booktitle = {},
  journal = {{J}ournal of {E}pidemiology and {C}ommunity {H}ealth},
  volume = {69},
  numero = {3},
  pages = {272--277},
  ISSN = {0143-005{X}},
  year = {2015},
  DOI = {10.1136/jech-2014-204678},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00012813},
}