Seblova V., Oury Bruno, Eddaikra N., Ait-Oudhia K., Pratlong F., Gazanion E., Maia C., Volf P., Sereno Denis
Source
Antimicrobial Agents and Chemotherapy, 2014,
58 (10), 6273-6276 ISSN 0066-4804
We studied the development of antimony-resistant Leishmania infantum in natural vectors Lutzomyia longipalpis and Phlebotomus perniciosus to ascertain the risk of parasite transmission by sand flies. All three resistant strains produced fully mature late-stage infections in sand flies; moreover, the resistant phenotype was maintained after the passage through the vector. These results highlight the risk of circulation of resistant Leishmania strains and question the use of human drugs for treatment of dogs as Leishmania reservoirs.
Plan de classement
Santé : généralités [050]
;
Entomologie médicale / Parasitologie / Virologie [052]
;
Sciences du monde animal [080]
