Publications des scientifiques de l'IRD

Gautret P., Benkouiten S., Parola P., Brouqui P., Memish Z., Raoult Didier. (2014). Occurrence of Tropheryma whipplei during diarrhea in Hajj pilgrims : a PCR analysis of paired rectal swabs. Travel Medicine and Infectious Disease, 12 (5), p. 481-484. ISSN 1477-8939.

Titre du document
Occurrence of Tropheryma whipplei during diarrhea in Hajj pilgrims : a PCR analysis of paired rectal swabs
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000343626700008
Auteurs
Gautret P., Benkouiten S., Parola P., Brouqui P., Memish Z., Raoult Didier
Source
Travel Medicine and Infectious Disease, 2014, 12 (5), p. 481-484 ISSN 1477-8939
Background: Tropheryma whipplei was recently associated with gastroenteritis in children. We hypothesize that T. whipplei may be a contributing microbe in traveller's diarrhea. Method: The presence of T. whipplei was investigated by PCR on rectal swab samples of Hajj pilgrims before and after travelling to the Kingdom of Saudi Arabia (KSA). Additionally a rectal swab was performed at the time of diarrhea for some pilgrims. Results: A total of 129 pilgrims underwent rectal swab samples before departure and on return. All pilgrims were negative for T. whipplei before travel. One pilgrim (0.8%) was positive on return but did not reported diarrhea. A total of 30 pilgrims (23.3%) experienced diarrhea during the stay in the KSA. Nine pilgrims with diarrhea underwent the additional rectal swab during their diarrhea episode, two of them were positive for T. whipplei. Conclusions: This work suggests that T. whipplei may be associated with adult traveller's diarrhea, by finding T. whipplei DNA individuals negative before and after the episode of diarrhea. Further study addressing this issue in larger cohorts of Hajj pilgrims with systematic sampling at the time of diarrheal episode may help to understand the potential role of T. whipplei in traveller's diarrhea.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052] ; Biotechnologies [084]
Description Géographique
ARABIE SAOUDITE
Localisation
Fonds IRD
Identifiant IRD
PAR00012385
Contact