%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Million, M.
%A Bellevegue, L.
%A Labussiere, A. S.
%A Dekel, M.
%A Ferry, T.
%A Deroche, P.
%A Socolovschi, C.
%A Cammilleri, S.
%A Raoult, Didier
%T Culture-negative prosthetic joint arthritis related to Coxiella burnetii
%D 2014
%L PAR00012302
%G ENG
%J American Journal of Medicine
%@ 0002-9343
%K Coxiella burnetii ; Culture-negative prosthetic joint arthritis ; Q fever
%M ISI:000341430000042
%N 8
%P 786.e7–786.e10
%R 10.1016/j.amjmed.2014.03.013
%U https://www.documentation.ird.fr/hor/PAR00012302
%V 127
%W Horizon (IRD)
%X BACKGROUND: The number of hip and knee arthroplasty procedures is steadily increasing as life expectancy increases. Coxiella burnetii may be responsible for culture-negative prosthetic joint arthritis and is associated with antibiotic failure and repeated surgeries. We report the first case series of C. burnetii-related culture-negative prosthetic joint arthritis. METHODS: Cases were retrieved from the French National Referral center for Q fever. Diagnosis was based on (18)fluorodeoxyglucose positron emission tomography, serology, broad-range polymerase chain reaction, and C. burnetii-specific polymerase chain reaction. RESULTS: Four cases of C. burnetii-related culture-negative prosthetic joint arthritis were found. Standard bacteriologic procedures would have missed the diagnosis in all cases. Etiologic diagnosis improved the outcome in all but 1 case. CONCLUSIONS: A systematic, comprehensive diagnostic strategy should be used in culture-negative prosthetic joint arthritis, including testing for C. burnetii in endemic areas.
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