@article{PAR00012302, title = {{C}ulture-negative prosthetic joint arthritis related to {C}oxiella burnetii}, author = {{M}illion, {M}. and {B}ellevegue, {L}. and {L}abussiere, {A}. {S}. and {D}ekel, {M}. and {F}erry, {T}. and {D}eroche, {P}. and {S}ocolovschi, {C}. and {C}ammilleri, {S}. and {R}aoult, {D}idier}, editor = {}, language = {{ENG}}, abstract = {{BACKGROUND}: {T}he number of hip and knee arthroplasty procedures is steadily increasing as life expectancy increases. {C}oxiella burnetii may be responsible for culture-negative prosthetic joint arthritis and is associated with antibiotic failure and repeated surgeries. {W}e report the first case series of {C}. burnetii-related culture-negative prosthetic joint arthritis. {METHODS}: {C}ases were retrieved from the {F}rench {N}ational {R}eferral center for {Q} fever. {D}iagnosis was based on (18)fluorodeoxyglucose positron emission tomography, serology, broad-range polymerase chain reaction, and {C}. burnetii-specific polymerase chain reaction. {RESULTS}: {F}our cases of {C}. burnetii-related culture-negative prosthetic joint arthritis were found. {S}tandard bacteriologic procedures would have missed the diagnosis in all cases. {E}tiologic diagnosis improved the outcome in all but 1 case. {CONCLUSIONS}: {A} systematic, comprehensive diagnostic strategy should be used in culture-negative prosthetic joint arthritis, including testing for {C}. burnetii in endemic areas.}, keywords = {{C}oxiella burnetii ; {C}ulture-negative prosthetic joint arthritis ; {Q} fever}, booktitle = {}, journal = {{A}merican {J}ournal of {M}edicine}, volume = {127}, numero = {8}, pages = {786.e7–786.e10}, ISSN = {0002-9343}, year = {2014}, DOI = {10.1016/j.amjmed.2014.03.013}, URL = {https://www.documentation.ird.fr/hor/{PAR}00012302}, }