@article{PAR00012135,
  title = {{I}nfective endocarditis : prevention, diagnosis, and management},
  author = {{T}huny, {F}. and {G}risoli, {D}. and {C}autela, {J}. and {R}iberi, {A}. and {R}aoult, {D}idier and {H}abib, {G}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}nfective endocarditis ({IE}) is among the most severe infectious disease, the prevention of which has not decreased its incidence. {T}he age of patients and the rate of health care-associated {IE} have increased as a consequence of medical progress. {T}he prevention strategies have been subjected to an important debate and nonspecific hygiene measures are now placed above the use of antibiotic prophylaxis. {I}ndeed, the level of evidence of antibiotic prophylaxis efficiency is low and the indications of its prescription have been restricted in the recent international guidelines. {I}n cases carrying a high suspicion of {IE}, efforts should be made to rapidly identify patients with a definite or highly probable diagnosis of {IE} and to find the causative pathogen to ensure that appropriate treatment, including urgent valvular surgery, begins promptly. {A}lthough echocardiography remains the main accurate imaging modality to identify endocardial lesions associated with {IE}, it can be negative or inconclusive especially in cases of prosthetic valve or other intracardiac devices. {R}ecent studies demonstrated the diagnostic value of other imaging strategies including cardiac computed tomography ({CT}), positron emission tomography/{CT}, radiolabelled leukocyte single-photon emission {CT}/{CT}, and cerebral magnetic resonance imaging. {N}ovel perspectives on the management of endocarditis are emerging and offer a hope for decreasing the rate of residual deaths by accelerating the processes of diagnosis, risk stratification, and instauration of antimicrobial therapy. {M}oreover, the rapid transfer of high-risk patients to specialized mediosurgical centres ({IE} team), the development of new surgical modalities, and close long-term follow-up are of crucial importance.},
  keywords = {},
  booktitle = {},
  journal = {{C}anadian {J}ournal of {C}ardiology},
  volume = {30},
  numero = {9},
  pages = {1046--1057},
  ISSN = {0828-282{X}},
  year = {2014},
  DOI = {10.1016/j.cjca.2014.03.042},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00012135},
}