@article{PAR00012133, title = {{N}egative impact of laws regarding biosecurity and bioterrorism on real diseases}, author = {{W}urtz, {N}. and {G}robusch, {M}. {P}. and {R}aoult, {D}idier}, editor = {}, language = {{ENG}}, abstract = {{R}esearch on highly pathogenic microorganisms in biosafety level 3 and 4 laboratories is very important for human public health, as it provides opportunities for the development of vaccines and novel therapeutics as well as diagnostic methods to prevent epidemics. {H}owever, in recent years, after the anthrax and {W}orld {T}rade {C}enter attacks in 2001 in the {USA}, the threat of bioterrorism has grown for both the public and the authorities. {A}s a result, technical and physical containment measures and biosafety and biosecurity practices have been implemented in laboratories handling these dangerous pathogens. {W}orking with selected biological agents and toxins is now highly regulated, owing to their potential to pose a threat to public health and safety, despite the fact that the anthrax attack was found to be the result of a lack of security at a {US} {A}rmy laboratory. {T}hus, these added regulations have been associated with a large amount of fruitless investment. {H}erein, we describe the limitations of research in these facilities, and the multiple consequences of the increased regulations. {T}hese limitations have seriously negatively impacted on the number of collaborations, the size of research projects, and, more generally, scientific research on microbial pathogens. {C}learly, the actual number of known victims and fatalities caused by the intentional use of microorganisms has been negligible as compared with those caused by naturally acquired human infections.}, keywords = {{B}iosafety ; biosafety laboratory ; biosecurity ; bioterrorism ; infectious ; disease ; laws ; limitations ; regulations ; select agent and toxins}, booktitle = {}, journal = {{C}linical {M}icrobiology and {I}nfection}, volume = {20}, numero = {6}, pages = {507--515}, ISSN = {1198-743{X}}, year = {2014}, DOI = {10.1111/1469-0691.12709}, URL = {https://www.documentation.ird.fr/hor/{PAR}00012133}, }