@article{PAR00012036, title = {{S}calp eschar and neck lymphadenopathy after tick bite : an emerging syndrome with multiple causes}, author = {{D}ubourg, {G}. and {S}ocolovschi, {C}. and {D}el {G}iudice, {P}. and {F}ournier, {P}. {E}. and {R}aoult, {D}idier}, editor = {}, language = {{ENG}}, abstract = {{T}he clinical and epidemiological features of 56 patients with scalp eschar associated with neck lymphadenopathy after a tick bite ({SENLAT}) syndrome were evaluated at the {N}ational {F}rench {R}ickettsial {C}enter. {E}schar swabs, crusts, and biopsies as well as ticks and blood samples were acquired for molecular and serological assays. {SENLAT} predominantly affects children (p < 0.05), followed by 40- to 70-year-olds, and it is found mostly in women (p < 0.05). {T}he seasonal distribution has two peaks: one in the spring (55%) and one in the autumn (30%). {T}he etiological agent was identified in 18 cases, which include {R}ickettsia slovaca in 13 cases with incidences of two co-infections with {R}ickettsia raoultii and one case caused by {R}ickettsia sibirica mongolitimonae. {O}ther possible agents that were found in attached ticks were {C}andidatus {R}. rioja, {C}oxiella burnetii, and {B}orrelia burgdorferi. {T}he tick vector was {D}ermacentor marginatus in almost all cases, with the exception of one case, in which {I}xodes ricinus was identified as the vector. {O}ur findings show that {SENLAT} is a clinical entity characterized as a local infection controlled by the immune system and is neither pathogen- nor vector-specific.}, keywords = {}, booktitle = {}, journal = {{E}uropean {J}ournal of {C}linical {M}icrobiology and {I}nfectious {D}iseases}, volume = {33}, numero = {8}, pages = {1449--1456}, ISSN = {0934-9723}, year = {2014}, DOI = {10.1007/s10096-014-2090-2}, URL = {https://www.documentation.ird.fr/hor/{PAR}00012036}, }