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Dubourg G., Socolovschi C., Del Giudice P., Fournier P. E., Raoult Didier. (2014). Scalp eschar and neck lymphadenopathy after tick bite : an emerging syndrome with multiple causes. European Journal of Clinical Microbiology and Infectious Diseases, 33 (8), p. 1449-1456. ISSN 0934-9723.

Titre du document
Scalp eschar and neck lymphadenopathy after tick bite : an emerging syndrome with multiple causes
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000338723600021
Auteurs
Dubourg G., Socolovschi C., Del Giudice P., Fournier P. E., Raoult Didier
Source
European Journal of Clinical Microbiology and Infectious Diseases, 2014, 33 (8), p. 1449-1456 ISSN 0934-9723
The clinical and epidemiological features of 56 patients with scalp eschar associated with neck lymphadenopathy after a tick bite (SENLAT) syndrome were evaluated at the National French Rickettsial Center. Eschar swabs, crusts, and biopsies as well as ticks and blood samples were acquired for molecular and serological assays. SENLAT predominantly affects children (p < 0.05), followed by 40- to 70-year-olds, and it is found mostly in women (p < 0.05). The seasonal distribution has two peaks: one in the spring (55%) and one in the autumn (30%). The etiological agent was identified in 18 cases, which include Rickettsia slovaca in 13 cases with incidences of two co-infections with Rickettsia raoultii and one case caused by Rickettsia sibirica mongolitimonae. Other possible agents that were found in attached ticks were Candidatus R. rioja, Coxiella burnetii, and Borrelia burgdorferi. The tick vector was Dermacentor marginatus in almost all cases, with the exception of one case, in which Ixodes ricinus was identified as the vector. Our findings show that SENLAT is a clinical entity characterized as a local infection controlled by the immune system and is neither pathogen- nor vector-specific.
Plan de classement
Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052] ; Biotechnologies [084]
Identifiant IRD
PAR00012036
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