@article{PAR00012034, title = {{D}oes {T}ropheryma whipplei contribute to travelers' diarrhea ? : a {PCR} analysis of paired stool samples in {F}rench travelers to {S}enegal}, author = {{G}autret, {P}. and {L}agier, {J}. {C}. and {B}enkouiten, {S}. and {F}enollar, {F}. and {R}aoult, {D}idier and {B}rouqui, {P}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {T}ropheryma whipplei was recently associated with acute infections as gastroenteritis in children. {W}e hypothesize that {T}. whipplei may be a contributing microbe in traveler's diarrhea. {M}ethod: {T}he presence of {T}. whipplei was investigated by using a specific {PCR} on stool samples of travelers to {S}enegal before and after traveling, independently of the occurrence of diarrhea. {R}esults: {A} total of 59 travelers returned both stool samples before and after travel and 16 (27%) experienced diarrhea during travel. {F}ifty-three patients (89.8%) were negative for {T}. whipplei before and after travel. {T}wo patients (3.4%) were negative before and positive after travel. {T}wo patients (3.4%) were positive before travel and negative after travel. {F}inally, two patients (3.4%) were positive before and after travel. {T}here were no carriage differences of {T}. whipplei, visiting {S}enegal or staying in {F}rance. {W}e found no significant association of {T}. whipplei carriage and travel-associated diarrhea but this may have been impacted by the use of doxycycline. {C}onclusions: {T}his is the first report of {T}. whipplei carriage acquired during travel to tropical area. {F}urther study addressing this issue in larger cohorts of travelers to {S}enegal, including individuals visiting friends and relatives in their country of origin and the protective role of doxycycline malaria chemoprophylaxis may help to understand the potential contribution of {T}. whipplei to travelers' diarrhea.}, keywords = {{D}iarrhea ; {T}raveler ; {S}enegal ; {T}topheryma whipplei ; {SENEGAL}}, booktitle = {}, journal = {{T}ravel {M}edicine and {I}nfectious {D}isease}, volume = {12}, numero = {3}, pages = {264--267}, ISSN = {1477-8939}, year = {2014}, DOI = {10.1016/j.tmaid.2014.01.009}, URL = {https://www.documentation.ird.fr/hor/{PAR}00012034}, }