@article{PAR00012032,
  title = {{K}nowledge translation : a case study on pneumonia research and clinical guidelines in a low-income country},
  author = {{G}oyet, {S}. and {B}arennes, {H}. and {L}ibourel, {T}h{\'e}r{\`e}se and van {G}riensven, {J}. and {F}rutos, {R}. and {T}arantola, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he process and effectiveness of knowledge translation ({KT}) interventions targeting policymakers are rarely reported. {I}n {C}ambodia, a low-income country ({LIC}), an intervention aiming to provide evidence-based knowledge on pneumonia to health authorities was developed to help update pediatric and adult national clinical guidelines. {T}hrough a case study, we assessed the effectiveness of this {KT} intervention, with the goal of identifying the barriers to {KT} and suggest strategies to facilitate {KT} in similar settings. {M}ethods: {A}n extensive search for all relevant sources of data documenting the processes of updating adult and pediatric pneumonia guidelines was done. {D}ocuments included among others, reports, meeting minutes, and email correspondences. {T}he study was conducted in successive phases: an appraisal of the content of both adult and pediatric pneumonia guidelines; an appraisal of the quality of guidelines by independent experts, using the {AGREE}-{II} instrument; a description and modeling of the {KT} process within the guidelines updating system, using the {U}nified {M}odeling {L}anguage ({UML}) tools 2.2; and the listing of the barriers and facilitators to {KT} we identified during the study. {R}esults: {T}he first appraisal showed that the integration of the {KT} key messages in pediatric and adult guidelines varied with a better efficiency in the pediatric guidelines. {T}he overall {AGREE}-{II} quality assessments scored 37% and 44% for adult and pediatric guidelines, respectively. {S}cores were lowest for the domains of `rigor of development' and `editorial independence.' {T}he {UML} analysis highlighted that time frames and constraints of the involved stakeholders greatly differed and that there were several missed opportunities to translate on evidence into the adult pneumonia guideline. {S}eventeen facilitating factors and 18 potential barriers to {KT} were identified. {M}ain barriers were related to the absence of a clear mandate from the {M}inistry of {H}ealth for the researchers and to a lack of synchronization between knowledge production and policy-making. {C}onclusions: {S}tudy findings suggest that stakeholders, both researchers and policy makers planning to update clinical guidelines in {LIC} may need methodological support to overcome the expected barriers.},
  keywords = {{K}nowledge translation ; {C}linical practice guideline ; {P}neumonia ; {L}ow-income country ; {CAMBODGE}},
  booktitle = {},
  journal = {{I}mplementation {S}cience},
  volume = {9},
  numero = {},
  pages = {art. 82},
  ISSN = {1748-5908},
  year = {2014},
  DOI = {10.1186/1748-5908-9-82},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00012032},
}