@article{PAR00012016, title = {{E}stimating the burden of {J}apanese {E}ncephalitis virus and other encephalitides in countries of the {M}ekong region}, author = {{T}arantola, {A}. and {G}outard, {F}. and {N}ewton, {P}. and de {L}amballerie, {X}avier and {L}ortholary, {O}. and {C}appelle, {J}. and {B}uchy, {P}.}, editor = {}, language = {{ENG}}, abstract = {{D}iverse aetiologies of viral and bacterial encephalitis are widely recognized as significant yet neglected public health issues in the {M}ekong region. {A} robust analysis of the corresponding health burden is lacking. {W}e retrieved 75 articles on encephalitis in the region published in {E}nglish or in {F}rench from 1965 through 2011. {R}eview of available data demonstrated that they are sparse and often derived from hospital-based studies with significant recruitment bias. {A}lmost half (35 of 75) of articles were on {J}apanese encephalitis virus ({JEV}) alone or associated with dengue. {I}n the {W}estern {P}acific region the {WHO} reported 30,000-50,000 annual {JEV} cases (15,000 deaths) between 1966 and 1996 and 4,633 cases (200 deaths) in 2008, a decline likely related to the introduction of {JEV} vaccination in {C}hina, {V}ietnam, or {T}hailand since the 1980s. {D}ata on dengue, scrub typhus and rabies encephalitis, among other aetiologies, are also reviewed and discussed. {C}ountries of the {M}ekong region are undergoing profound demographic, economic and ecological change. {A}s the epidemiological aspects of {J}apanese encephalitis ({JE}) are transformed by vaccination in some countries, highly integrated expert collaborative research and objective data are needed to identify and prioritize the human health, animal health and economic burden due to {JE} and other pathogens associated with encephalitides.}, keywords = {{MEKONG} ; {VIET} {NAM} ; {THAILANDE} ; {CHINE} ; {CAMBODGE}}, booktitle = {}, journal = {{P}los {N}eglected {T}ropical {D}iseases}, volume = {8}, numero = {1}, pages = {e2533}, ISSN = {1935-2735}, year = {2014}, DOI = {10.1371/journal.pntd.0002533}, URL = {https://www.documentation.ird.fr/hor/{PAR}00012016}, }