@article{PAR00011797, title = {{Z}amilon, a novel virophage with mimiviridae host specificity}, author = {{G}aia, {M}. and {B}enamar, {S}. and {B}oughalmi, {M}. and {P}agnier, {I}. and {C}roce, {O}. and {C}olson, {P}. and {R}aoult, {D}idier and {L}a {S}cola, {B}.}, editor = {}, language = {{ENG}}, abstract = {{V}irophages, which are potentially important ecological regulators, have been discovered in association with members of the order {M}egavirales. {S}putnik virophages target the {M}imiviridae, {M}avirus was identified with the {C}afeteria roenbergensis virus, and virophage genomes reconstructed by metagenomic analyses may be associated with the {P}hycodnaviridae. {D}espite the fact that the {S}putnik virophages were isolated with viruses belonging to group {A} of the {M}imiviridae, they can grow in amoebae infected by {M}imiviridae from groups {A}, {B} or {C}. {I}n this study we describe {Z}amilon, the first virophage isolated with a member of group {C} of the {M}imiviridae family. {B}y co-culturing amoebae with purified {Z}amilon, we found that the virophage is able to multiply with members of groups {B} and {C} of the {M}imiviridae family but not with viruses from group {A}. {Z}amilon has a 17,276 bp {DNA} genome that potentially encodes 20 genes. {M}ost of these genes are closely related to genes from the {S}putnik virophage, yet two are more related to {M}egavirus chiliensis genes, a group {B} {M}imiviridae, and one to {M}oumouvirus monve transpoviron.}, keywords = {}, booktitle = {}, journal = {{P}los {O}ne}, volume = {9}, numero = {4}, pages = {e94923}, ISSN = {1932-6203}, year = {2014}, DOI = {10.1371/journal.pone.0094923}, URL = {https://www.documentation.ird.fr/hor/{PAR}00011797}, }