@article{PAR00011687,
  title = {{V}iruses in a 14th-century coprolite},
  author = {{A}ppelt, {S}. and {F}ancello, {L}. and {L}e {B}ailly, {M}. and {R}aoult, {D}idier and {D}rancourt, {M}. and {D}esnues, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}oprolites are fossilized fecal material that can reveal information about ancient intestinal and environmental microbiota. {V}iral metagenomics has allowed systematic characterization of viral diversity in environmental and human-associated specimens, but little is known about the viral diversity in fossil remains. {H}ere, we analyzed the viral community of a 14th-century coprolite from a closed barrel in a {M}iddle {A}ges site in {B}elgium using electron microscopy and metagenomics. {V}iruses that infect eukaryotes, bacteria, and archaea were detected, and we confirmed the presence of some of them by ad hoc suicide {PCR}. {T}he coprolite {DNA} viral metagenome was dominated by sequences showing homologies to phages commonly found in modern stools and soil. {A}lthough their phylogenetic compositions differed, the metabolic functions of the viral communities have remained conserved across centuries. {A}ntibiotic resistance was one of the reconstructed metabolic functions detected.},
  keywords = {},
  booktitle = {},
  journal = {{A}pplied and {E}nvironmental {M}icrobiology},
  volume = {80},
  numero = {9},
  pages = {2648--2655},
  ISSN = {0099-2240},
  year = {2014},
  DOI = {10.1128/aem.03242-13},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00011687},
}