Publications des scientifiques de l'IRD

Edouard S., Million M., Royer G., Giorgi R., Grisoli D., Raoult Didier. (2014). Reduction in incidence of Q fever endocarditis : 27 years of experience of a national reference center. Journal of Infection, 68 (2), p. 141-148. ISSN 0163-4453.

Titre du document
Reduction in incidence of Q fever endocarditis : 27 years of experience of a national reference center
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000329581000005
Auteurs
Edouard S., Million M., Royer G., Giorgi R., Grisoli D., Raoult Didier
Source
Journal of Infection, 2014, 68 (2), p. 141-148 ISSN 0163-4453
Objectives: We conducted an observational study to evaluate the impact of our antibioprophylaxis protocols implemented in 2000, on the incidence of Q fever endocarditis diagnosed in our French reference center between 1985 and 2011. Methods: Endocarditis was diagnosed according to modified Duke Criteria, serological and PCR results. Our prophylaxis recommendations consist of a systematic echocardiography and an antibioprophylaxis in patients with acute Q fever and risk factors for developing endocarditis. Results: Over the last 27 years, we diagnosed 4231 acute Q fever and 818 endocarditis. Despite a significantly increased number of acute Q fever diagnoses and the use of systematic PCR testing of valves allowing serendipitous Q fever endocarditis diagnoses, we observed a decline of Q fever endocarditis. The number of cases has decreased from 316, which represents 18% of newly diagnosed cases of Q fever between 1998 and 2004, to 225, which corresponds to 11% of the cases diagnosed between 2005 and 2011. Conclusion: We believe that this decrease was a result of our strategies for prophylaxis. If this assumption is true, we may have prevented more than 150 cases of Q fever endocarditis in France over the past 10 years.
Plan de classement
Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
FRANCE
Localisation
Fonds IRD
Identifiant IRD
PAR00011394
Contact