@article{PAR00011268, title = {{M}arseillevirus prevalence in multitransfused patients suggests blood transmission}, author = {{P}opgeorgiev, {N}. and {C}olson, {P}. and {T}huret, {I}. and {C}hiarioni, {J}. and {G}allian, {P}. and {R}aoult, {D}idier and {D}esnues, {C}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {E}merging viral infections in humans are appearing at an increasing rate. {R}ecently, we identified a new {M}arseillevirus, named {G}iant {B}lood {M}arseillevirus ({GBM}), by performing viral metagenomics on asymptomatic blood donors. {O}bjectives: {T}o study and compare the prevalence of {M}arseillevirus between asymptomatic blood donors and thalassemia patients. {D}esign: {H}ere, we present a combined molecular and serological study on 174 asymptomatic blood donors and 22 patients with thalassemia who receive repeated blood transfusions to estimate the prevalence of {M}arseillevirus in these two populations. {R}esults: {W}e identified {M}arseillevirus genomic {DNA} in 4% of donors, whereas 9.1% of the thalassemia patients were positive for this virus. {M}oreover, {I}g{G} seropositivity was detected in 22.7% of patients in the thalassemia group, whereas this seropositivity was observed in 12.6% of the blood donor population. {C}onclusion: {T}hese results suggest that {M}arseillevirus infection is not rare in healthy persons and may be transmitted by transfusion, thus raising speculation regarding the long-term consequences of this viral infection, particularly in patients requiring repeated blood transfusions.}, keywords = {{G}iant viruses ; {B}lood donors ; {B}lood infection ; {T}halassemia ; {T}ransfusion}, booktitle = {}, journal = {{J}ournal of {C}linical {V}irology}, volume = {58}, numero = {4}, pages = {722--725}, ISSN = {1386-6532}, year = {2013}, DOI = {10.1016/j.jcv.2013.10.001}, URL = {https://www.documentation.ird.fr/hor/{PAR}00011268}, }