@article{PAR00011181,
  title = {{C}orrelation between body mass index and gut concentrations of {L}actobacillus reuteri, {B}ifidobacterium animalis, {M}ethanobrevibacter smithii and {E}scherichia coli},
  author = {{M}illion, {M}. and {A}ngelakis, {E}. and {M}araninchi, {M}. and {H}enry, {M}. and {G}iorgi, {R}. and {V}alero, {R}. and {V}ialettes, {B}. and {R}aoult, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{BACKGROUND}: {G}enus and species level analysis is the best way to characterize alterations in the human gut microbiota that are associated with obesity, because the clustering of obese and lean microbiotas increases with the taxonomic depth of the analysis. {B}ifidobacterium genus members have been associated with a lean status, whereas different {L}actobacillus species are associated both with a lean and an obese status. {OBJECTIVES} {AND} {METHODS}: {W}e analyzed the fecal concentrations of {B}acteroidetes, {F}irmicutes, {M}ethanobrevibacter smithii, the genus {L}actobacillus, five other {L}actobacillus species previously linked with lean or obese populations, {E}scherichia coli and {B}ifidobacterium animalis in 263 individuals, including 134 obese, 38 overweight, 76 lean and 15 anorexic subjects to test for the correlation between bacterial concentration and body mass index ({BMI}). {O}f these subjects, 137 were used in our previous study. {FINDINGS}: {F}irmicutes were found in >98.5%, {B}acteroidetes in 67%, {M}. smithii in 64%, {E}. coli in 51%, {L}actobacillus species between 17 and 25% and {B}. animalis in 11% of individuals. {T}he fecal concentration of {L}actobacillus reuteri was positively correlated with {BMI} (coefficient 0.85; 95% confidence interval ({CI}) 0.12-0.58; {P}= 0.02) in agreement with what was reported for {L}actobacillus sakei. {A}s reported, {B}. animalis (coefficient = - 0.84; 95% {CI} - 1.61 to - 0.07; {P}= 0.03) and {M}. smithii (coefficient = - 0.43, 95% {CI} - 0.90 to 0.05; {P} 0.08) were negatively associated with the {BMI}. {U}nexpectedly, {E}. coli was found here for the first time to negatively correlate with the {BMI} (coefficient = - 1.05; 95% {CI} - 1.60 to - 0.50; {P}<0.001). {CONCLUSION}: {O}ur findings confirm the specificity of the obese microbiota and emphasize the correlation between the concentration of certain {L}actobacillus species and obesity.},
  keywords = {body mass index ; {L}actobacillus ; {B}ifidobacterium ; probiotics ; {M}ethanobrevibacter smithii ; {E}scherichia coli},
  booktitle = {},
  journal = {{I}nternational {J}ournal of {O}besity},
  volume = {37},
  numero = {11},
  pages = {1460--1466},
  ISSN = {0307-0565},
  year = {2013},
  DOI = {10.1038/ijo.2013.20},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00011181},
}