@article{PAR00011046,
  title = {{T}he origin and molecular epidemiology of {HIV}},
  author = {{P}eeters, {M}artine and {J}ung, {M}. and {A}youba, {A}hidjo},
  editor = {},
  language = {{ENG}},
  abstract = {{HIV}-1 in humans resulted from at least four cross-species transmissions of simian immunodeficiency viruses ({SIV}s) from chimpanzees and gorillas in {W}est {C}entral {A}frica, while {HIV}-2 viruses resulted from at least eight independent transmissions of {SIV}s infecting sooty mangabeys in {W}est {A}frica only, where one of these transmissions ({HIV}-1 group {M}) is responsible for the global epidemic. {HIV}-1 {M} is subdivided into nine subtypes and a wide diversity of circulating recombinant forms ({CRF}s) and unique recombinant forms. {T}he heterogenic {HIV}-1 {M} subtype/{CRF} distribution is the result of founder effects. {T}he genetic diversity of {HIV}-1 continues to increase overtime due to demographic factors such as travel and migration and frequent co/superinfections. {I}n addition, the expanded access to antiretrovirals leads to an increasing number of drug-resistant strains, especially in resource limited countries.},
  keywords = {cross-species transmission ; drug resistance ; evolution ; {HIV}-1 ; {HIV}-2 ; molecular epidemiology ; recombinant ; {SIV} ; subtype ; {AFRIQUE} {CENTRALE} ; {AFRIQUE} {DE} {L}'{OUEST}},
  booktitle = {},
  journal = {{E}xpert {R}eview of {A}nti-{I}nfective {T}herapy},
  volume = {11},
  numero = {9},
  pages = {885--896},
  ISSN = {1478-7210},
  year = {2013},
  DOI = {10.1586/14787210.2013.825443},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00011046},
}