@article{PAR00010935,
  title = {{I}mpaired virulence and fitness of a colistin-resistant clinical isolate of {A}cinetobacter baumannii in a rat {M}odel of pneumonia},
  author = {{H}raiech, {S}. and {R}och, {A}. and {L}epidi, {H}. and {A}tieh, {T}. and {A}udoly, {G}. and {R}olain, {J}. {M}. and {R}aoult, {D}idier and {B}runel, {J}. {M}. and {P}apazian, {L}. and {B}regeon, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e compared the fitness and lung pathogenicity of two isogenic clinical isolates of {A}cinetobacter baumannii, one resistant ({ABCR}) and the other susceptible ({ABCS}) to colistin. {I}n vitro, {ABCR} exhibited slower growth kinetics than {ABCS}. {I}n a rat model of pneumonia, {ABCR} was associated with less pronounced signs of infection (lung bacterial count, systemic dissemination, and lung damage) and a better outcome ({ABCR} and {ABCS} mortality rates, 20 and 50%, respectively [{P} = 0.03]).},
  keywords = {},
  booktitle = {},
  journal = {{A}ntimicrobial {A}gents and {C}hemotherapy},
  volume = {57},
  numero = {10},
  pages = {5120--5121},
  ISSN = {0066-4804},
  year = {2013},
  DOI = {10.1128/aac.00700-13},
  URL = {https://www.documentation.ird.fr/hor/{PAR}00010935},
}