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Colson P., Pagnier I., Yoosuf N., Fournous G., La Scola B., Raoult Didier. (2013). "Marseilleviridae", a new family of giant viruses infecting amoebae. Archives of Virology, 158 (4), p. 915-920. ISSN 0304-8608.

Titre du document
"Marseilleviridae", a new family of giant viruses infecting amoebae
Année de publication
2013
Type de document
Article référencé dans le Web of Science WOS:000317305200022
Auteurs
Colson P., Pagnier I., Yoosuf N., Fournous G., La Scola B., Raoult Didier
Source
Archives of Virology, 2013, 158 (4), p. 915-920 ISSN 0304-8608
The family "Marseilleviridae" is a new proposed taxon for giant viruses that infect amoebae. Its first member, Acanthamoeba polyphaga marseillevirus (APMaV), was isolated in 2007 by culturing on amoebae a water sample collected from a cooling tower in Paris, France. APMaV has an icosahedral shape with a diameter of a parts per thousand 250 nm. Its genome is a double-stranded circular DNA that is 368,454 base pairs (bp) in length. The genome has a GC content of 44.7 % and is predicted to encode 457 proteins. Phylogenetic reconstructions showed that APMaV belongs to a new viral family among nucleocytoplasmic large DNA viruses, a group of viruses that also includes Acanthamoeba polyphaga mimivirus (APMV) and the other members of the family Mimiviridae as well as the members of the families Poxviridae, Phycodnaviridae, Iridoviridae, Ascoviridae, and Asfarviridae. In 2011, Acanthamoeba castellanii lausannevirus (ACLaV), another close relative of APMaV, was isolated from river water in France. The ACLaV genome is 346,754 bp in size and encodes 450 genes, among which 320 have an APMaV protein as the closest homolog. Two other giant viruses closely related to APMaV and ACLaV have been recovered in our laboratory from a freshwater sample and a human stool sample using an amoebal co-culture method. The only currently identified hosts for "marseilleviruses" are Acanthamoeba spp. The prevalence of these viruses in the environment and in animals and humans remains to be determined.
Plan de classement
Entomologie médicale / Parasitologie / Virologie [052]
Identifiant IRD
PAR00010418
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