Slimani M., Pagnier I., Raoult Didier, La Scola B. (2013). Amoebae as battlefields for bacteria, giant viruses, and virophages. Journal of Virology, 87 (8), p. 4783-4785. ISSN 0022-538X.
Titre du document
Amoebae as battlefields for bacteria, giant viruses, and virophages
Slimani M., Pagnier I., Raoult Didier, La Scola B.
Source
Journal of Virology, 2013,
87 (8), p. 4783-4785 ISSN 0022-538X
When amoebae are simultaneously infected with Acanthamoeba polyphaga Mimivirus (APM) and the strictly intracellular BABL1 bacterium, the latter is always lost after serial subculturing. We showed that the virophage Sputnik 1, by reducing APM fitness, preserved BABL1 growth in acute and chronic models. This capability of a virophage to modulate the virulence of mimiviruses highlights the competition that occurs between them during natural host infection.
