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Keita A. K., Raoult Didier, Fenollar F. (2013). Tropheryma whipplei as a commensal bacterium. Future Microbiology, 8 (1), p. 57-71. ISSN 1746-0913.

Titre du document
Tropheryma whipplei as a commensal bacterium
Année de publication
2013
Type de document
Article référencé dans le Web of Science WOS:000314578700012
Auteurs
Keita A. K., Raoult Didier, Fenollar F.
Source
Future Microbiology, 2013, 8 (1), p. 57-71 ISSN 1746-0913
Tropheryma whipplei is the bacterial agent of the well-known and rare Whipple's disease, mainly observed among Caucasians. This bacterium has recently been involved in other chronic and acute infections. For a long time, the only known source of the bacterium was patients with Whipple's disease; however, thanks to the advent of molecular biology, T. whipplei has now been detected in specimens from healthy individuals, mainly in stool and saliva samples. The prevalence of carriage depends on several factors, such as age, exposure and geographical area, reaching 75% in stool specimens from children less than 4 years old in rural Africa. T. whipplei is a commensal bacterium that only causes Whipple's disease in a subset of individuals, probably those with a still-uncharacterized specific immunological defect.
Plan de classement
Santé : généralités [050] ; Biotechnologies [084]
Identifiant IRD
PAR00010212
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