%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Calattini, S. %A Betsem, E. %A Bassot, S. %A Chevalier, S. A. %A Mahieux, R. %A Froment, Alain %A Gessain, A. %T New strain of Human T Lymphotropic Virus (HTLV) type 3 in a pygmy from Cameroon with peculiar HTLV serologic results %D 2009 %L PAR00003580 %G ENG %J journal of Infectious Diseases %K CAMEROUN %M ISI:000262802200013 %N 4 %P 561-564 %R 10.1086/596206 %U https://www.documentation.ird.fr/hor/PAR00003580 %> https://www.documentation.ird.fr/intranet/publi/depot/2013-03-18/010058426.pdf %V 199 %W Horizon (IRD) %X A search for human T lymphotropic virus (HTLV) types 1 and 2 and related viruses was performed by serological and molecular means on samples obtained from 421 adult villagers from the southern Cameroon forest areas. One individual (a 56-year-old Baka Pygmy hunter) was found to be HTLV-3 infected; however, there was a low proviral load in blood cells. Complete sequence analysis of this virus (HTLV-3(Lobak18)) indicated a close relationship to human HTLV-3(Pyl43) and simian STLV-3(CTO604) strains. Plasma samples from Lobak18, the HTLV-3 infected individual, exhibited a peculiar "HTLV-2-like" pattern on Western blot analysis and were serologically untypeable by line immunoassay. These results were different from those for the 2 previously reported HTLV-3 strains, raising questions about serological confirmation of infection with such retroviruses. %$ 052